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Sexual and pelvic health

Libido, vaginal and bladder health, and pelvic floor changes.

Pelvic health

Genitourinary syndrome of menopause (GSM): symptoms and treatment

GSM is the vaginal, vulvar, and urinary change caused by falling estrogen. Learn the symptoms, how it is diagnosed, and which treatments work best.
Pelvic health

Low sex drive in perimenopause: what is going on and what helps

Why desire often drops in perimenopause, how hormones, sleep, mood, pain, and relationships interact, and which treatments have evidence, including flibanserin.
Pelvic health

Painful sex in perimenopause: causes and treatments

Why sex can start to hurt in perimenopause, from vaginal dryness to pelvic floor tension, and the treatments that help, including lubricants, estrogen, and PT.
Pelvic health

Pelvic floor physical therapy: what it is and who it helps

What happens in pelvic floor physical therapy, which midlife problems it helps, from bladder leaks to painful sex and prolapse, and what the trials show.
Pelvic health

Recurrent UTIs after 40: why they happen and how to prevent them

Why bladder infections keep coming back after 40, and the prevention steps with evidence: vaginal estrogen, cranberry, methenamine, more water, and antibiotics.
Pelvic health

Bladder leaks when you laugh or cough: stress incontinence

Why you leak urine when you laugh, cough, or exercise, how common stress incontinence is at midlife, and what works, from pelvic floor training to surgery.
Pelvic health

Testosterone for low libido in women: what the evidence says

What the evidence says about testosterone for low libido in women: who it helps, how much, the safety gaps, and why no US product is FDA-approved for women.
Pelvic health

Vaginal dryness treatments: from moisturizers to vaginal estrogen

Vaginal dryness treatments compared: lubricants, moisturizers, vaginal estrogen, DHEA, and ospemifene, with what the trials show and where to start.

Overview

Falling estrogen changes the tissues of the vagina, vulva and bladder, a condition called genitourinary syndrome of menopause (GSM). It can cause dryness, burning, pain with sex, urinary urgency and repeated bladder infections, and unlike hot flashes it usually gets worse over time without treatment. Desire often shifts too, for reasons that go beyond hormones. These problems are common, rarely discussed and very treatable.

Where to start

For the full picture of what falling estrogen does to these tissues and how it is treated, start with genitourinary syndrome of menopause. If dryness is the main issue, vaginal dryness treatments compares the options from moisturizers to vaginal estrogen. If sex has started to hurt, read painful sex in perimenopause, and if desire is the concern, low sex drive in perimenopause.

Common problems at a glance

ProblemWhat it feels likeWhat has evidenceRead the guide
Vaginal drynessDryness, burning or irritation day to dayMoisturizers and lubricants first; low-dose vaginal estrogen for moderate to severe symptomsVaginal dryness treatments
Painful sexPain at the entrance or deeper, often with muscle guardingTreatment matched to the cause, including vaginal estrogen, DHEA, ospemifene and pelvic floor therapyPainful sex in perimenopause
Low desireLess interest in sex that bothers youFixing pain, sleep, mood and medication issues first; flibanserin; testosterone off-label after menopauseLow sex drive
Testosterone questionsWondering whether low testosterone is the causeEvidence only for postmenopausal women with diagnosed low-desire disorder; no FDA-approved product for womenTestosterone and libido
Recurrent UTIsTwo or more infections in six months, or three in a yearA urine culture each time; vaginal estrogen; cranberry; methenamineRecurrent UTIs after 40
Bladder leaksLeaking when you laugh, cough or exercisePelvic floor muscle training first; weight loss if overweight; devices or surgery if leaks persistStress incontinence

What the evidence says

Over-the-counter moisturizers, used two or three times a week, and lubricants, used at the time of sex, are first-line for mild symptoms; vaginal moisturizers and lubricants explains how to choose them. Low-dose vaginal estrogen has the strongest evidence for moderate to severe symptoms, and cream, tablet and ring forms work about equally well. Most treatments help within a few weeks, can take 12 weeks for full effect and stop working when you stop.

Pelvic floor physical therapy is the first-line treatment for stress incontinence: in trials, 56% of women who did pelvic floor muscle training reported cure, versus 6% without treatment. Trials also show benefit for prolapse symptoms, and a small trial found less pain with sex. Vaginal laser and radiofrequency treatments are not supported by current evidence, and supplements have not been shown to help dryness.

When to see a clinician

See a clinician if dryness, pain with sex or urinary symptoms are bothering you; an OB-GYN can examine you and rule out infection, skin conditions and other causes. Seek care promptly for a urinary infection with fever, back or side pain, or vomiting, and report any bleeding after menopause. The symptom check can help you raise these topics at the visit, and you can find an OB-GYN near you or browse the directory.

Frequently asked questions

Can perimenopause cause vaginal dryness?

Yes. Vaginal dryness is part of genitourinary syndrome of menopause (GSM), which is driven by falling estrogen and can begin during perimenopause. In SWAN, vaginal dryness was reported by 19.4% of women aged 42 to 53 and by 34.0% of the same group by ages 57 to 69. You do not need to wait for your periods to stop to get treatment.

Why is my sex drive lower in perimenopause?

Hormones are one piece, rarely the whole story. In SWAN, desire declined by late perimenopause even after accounting for age and health, but overall health, psychological well-being and how important sex was to each woman were linked to every aspect of sexual function. Pain with sex, night sweats and poor sleep, depression, medications and relationship strain are common, fixable contributors.

Is vaginal estrogen safe?

For most women, the evidence is reassuring. Low-dose vaginal estrogen acts mainly on vaginal and urinary tissue, and blood estrogen levels generally stay in the postmenopausal range. Large cohort studies found no higher risk of heart disease or cancer, a progestogen is not needed, and in November 2025 the FDA asked manufacturers to remove those risks from its boxed warning.

Why do I keep getting UTIs after 40?

Estrogen supports the lactobacilli that keep the vagina acidic and crowd out bowel bacteria. As estrogen falls, bacteria such as E. coli can colonize the area near the urethra. The American Urological Association recommends vaginal estrogen for perimenopausal and postmenopausal women with recurrent UTIs, along with a urine culture for each episode.

  1. The NAMS 2020 GSM Position Statement Editorial Panel. The 2020 genitourinary syndrome of menopause position statement of The North American Menopause Society. Menopause, 2020
  2. American Urological Association. Genitourinary Syndrome of Menopause: AUA/SUFU/AUGS Guideline (2025)
  3. Avis NE, et al. Longitudinal changes in sexual functioning as women transition through menopause: results from the Study of Women's Health Across the Nation. Menopause, 2009
  4. Dumoulin C, et al. Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women. Cochrane Database of Systematic Reviews, 2018

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